Endothelial Function in Obstructive Sleep Apnea
نویسندگان
چکیده
منابع مشابه
Endothelial function in obstructive sleep apnea and response to treatment.
Impaired endothelium-dependent vascular relaxation is a prognostic marker of atherosclerosis and cardiovascular disease. We evaluated endothelium-dependent flow-mediated dilation (FMD) and endothelium-independent nitroglycerin (NTG)-induced dilation of the brachial artery with Doppler ultrasound in 28 men with obstructive sleep apnea (OSA) and 12 men without OSA. Subjects with OSA (apnea-hypopn...
متن کاملPredictors of impaired endothelial function in obstructive sleep apnea syndrome.
OBJECTIVES Obstructive sleep apnea syndrome (OSA) is associated with increased cardiovascular morbidity and mortality. Endothelial dysfunction (ED), accelerated atherosclerosis and autonomic dysfunction might be the key players responsible for development of vascular diseases in patients with OSA. In a population with suspected OSA and low burden of cardiovascular risk factors, we therefore aim...
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BACKGROUND Obstructive sleep apnea (OSA) occurs in 4% of middle-aged men and 2% of middle-aged women in the general population, and the prevalence is even higher in specific patient groups. OSA is an independent risk factor for a variety of cardiovascular diseases. Endothelial injury could be the pivotal determinant in the development of cardiovascular pathology in OSA. Endothelial damage ultim...
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Is OSA Associated with a Decline in NCF? The data regarding associations between OSA and a NCF decline are mixed. Some of the limitations of evaluating existing studies in the literature are that a majority have small sample sizes, a diverse group of NCF tests and protocols have been reported, and in the case of controlled trials, different shams or placebos have been utilized. There are severa...
متن کاملOxidative stress inflammation and endothelial dysfunction in obstructive sleep apnea.
Obstructive sleep apnea syndrome (OSA) is a breathing disorder in sleep. In recent years, this entity has emerged as a major public health problem due to its high prevalence and the profound impact on patients' health and quality of life. A large body of evidence identified OSA as an independent risk factor for cardiovascular morbidity and mortality. Also an association was demonstrated with ad...
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ژورنال
عنوان ژورنال: Progress in Cardiovascular Diseases
سال: 2009
ISSN: 0033-0620
DOI: 10.1016/j.pcad.2008.08.002